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PHYTOR RESTORE LUNG ACTIVE INGREDIENTS

Each of our chosen Herbs Contain in Excess of 3,000 Plant Compounds

From these we have isolated specific active ingredients which deliver targeted health benefits. We have shared our herbal formulations with over 10,000 patients who seek to use natural remedies to support their body’s natural healing abilities.

CLINACANTHUS NUTANS

Traditionally used as herbal medicines in Thailand, Malaysia, Indonesia and China, extensive studies on the herb had started since the late 1980s. The herb has been of great interest to researchers for its folk use in various diseases such as kidney and liver issues, irregular periods, skin rashes, varicella-zoster virus lesions, dysentery and cancer.

Chinese Name: 忧遁草 Yōu dùn cǎo

Contains stigmasterol, lupeol, β-Sitosterol, betulin, C-glycosyl flavones (vitexin, isovitexin, shaftoside, isomollupentin 7-O-β-glucopyranoside, orientin and isoorientin), nine cerebrosides and monoacylmonogalactoylglycerol; as well as chlorophyll derivatives.

Native: Thailand, Malaysia, Indonesia, China

Habitat: Wet forests and plains, mainly cultivated.

Plant Description: Scandent shrub with upright branches and narrow, oblong leaves.

Please refer to the published research

Please refer to the published research

  • Ong, W. Y., Herr, D. R., Sun, G. Y., & Lin, T. N. (2022). Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans. Molecules27(11), 3607. DOI: https://doi.org/10.3390/molecules27113607
  • Chia, T. Y., Gan, C. Y., Murugaiyah, V., Hashmi, S. F., Fatima, T., Ibrahim, L., … & Ahmad, A. (2021). A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine. Molecules27(1), 139. DOI:https://doi.org/10.3390/molecules27010139
  • Mahmod, I. I., Ismail, I. S., Alitheen, N. B., Normi, Y. M., Abas, F., Khatib, A., & Latip, J. (2020). NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition. BMC complementary medicine and therapies20(1), 1-18. DOI: http://dx.doi.org/10.1186/s12906-020-03067-3
  • Alam, A., Ferdosh, S., Ghafoor, K., Hakim, A., Juraimi, A. S., Khatib, A., & Sarker, Z. I. (2016). Clinacanthus nutans: A review of the medicinal uses, pharmacology and phytochemistry. Asian Pacific journal of tropical medicine9(4), 402-409. DOI:https://doi.org/10.1016/j.apjtm.2016.03.011

LEEA INDICA

Leea Indica, otherwise known as “Bandicoot Berry” is a large shrub in the family Vitaceae – a plant family known for its fruit crop. The whole plant is traditionally used in India to treat headache, joint or body pain, rheumatism and skin issues.  It was one of the seven medicinal plants studied by a team of NUS researchers over 3-years period between 2010 and 2013 for potential cancer-fighting properties. 

Chinese Name: 火筒树 Huǒ tǒng shù

Contains 31 compounds of different classes, including β-Sitosterol, Lupeol, Di-n-octyl, β-Amyrin, Gallic acid, Quercitrin, Dibutyl phthalate, α-Tocopherol, Di-iso butyl phthalate, Di-n-butyl phthalate, N-butyl iso butyl phthalate, Mollic acid arabinoside, Phthalic acid, Palmitic acid, Eicosanol, Solanesol, Farnesol, Ursolic acid and N-butyl gallate.

Native: Indomalaya, Indochina, Australia, Pacific Islands

Habitat: Wet forests and plains, mainly cultivated.

Plant Description: Large evergreen perennial shrubs with twice or thrice pinnate leaves.

Please refer to the published research

Please refer to the published research

  • Siew, Y. Y., Yew, H. C., Neo, S. Y., Seow, S. V., Lew, S. M., Lim, S. W., … & Koh, H. L. (2019). Evaluation of anti-proliferative activity of medicinal plants used in Asian Traditional Medicine to treat cancer. Journal of ethnopharmacology, 235, 75-87. https://doi.org/10.1016/j.jep.2018.12.040

  • Mishra, G., Khosa, R. L., Singh, P., & Tahseen, M. A. (2016b). Ethnobotany and phytopharmacology of Leea indica: An overview. Journal of Coastal Life Medicine, 4(1), 69–72. https://doi.org/10.12980/jclm.4.2016jclm-2014-0017

  • Rahman, M. A., Imran, T. B., & Islam, S. (2013). Antioxidative, antimicrobial and cytotoxic effects of the phenolics of Leea indica leaf extract. Saudi Journal of Biological Sciences, 20(3), 213–225. https://doi.org/10.1016/j.sjbs.2012.11.007

  • Hossain, F., Mostofa, M. G., & Alam, A. K. (2021). Traditional uses and pharmacological activities of the genus leea and its phytochemicals: A review. Heliyon, 7(2), e06222. https://doi.org/10.1016/j.heliyon.2021.e06222

  • Singh, D., Siew, Y. Y., Chong, T. I., Yew, H. C., Ho, S. S. W., Lim, C. S. E. S., … & Koh, H. L. (2019). Identification of phytoconstituents in Leea indica (Burm. F.) Merr. leaves by high performance liquid chromatography micro time-of-flight mass spectrometry. Molecules, 24(4), 714. https://doi.org/10.3390/molecules24040714

Strobilanthes crispus

Traditionally used in Indonesia and Malaysia to treat urinary stones, gallbladder stones, difficult urination, hemorrhoid, constipation,  or for diuretic purpose. It was one of the seven medicinal plants studied by a team of NUS researchers over 3-years period between 2010 and 2013 for potential cancer-fighting properties.

Chinese Name: 黑面将军 Hēi miàn jiāng jūn

Contains p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, vanillic acid, gentinic acid, ferulic acid, syryngic acid, tannin alkaloid, catechin, rutin, myricetin, luteolin, apigenin, naringenin and kaempferol

Native: Madagascar, Indonesia, Malaysia

Plant Description: Shrub with dark green shiny leaves occurring in pairs in opposite leaf arrangement.

Please refer to the published research

Please refer to the published research

  • Chong, H. Z., Rahmat, A., Yeap, S. K., Md Akim, A., Alitheen, N. B., Othman, F., & Gwendoline-Ee, C. L. (2012). In vitro cytotoxicity of Strobilanthes crispus ethanol extract on hormone dependent human breast adenocarcinoma MCF-7 cell. BMC Complementary and Alternative Medicine, 12(1). https://doi.org/10.1186/1472-6882-12-35

  • Ng, M. G., Ng, C. H., Ng, K. Y., Chye, S. M., Ling, A. P. K., & Koh, R. Y. (2021). Anticancer Properties of Strobilanthes crispus: A Review. Processes, 9(8), 1370. https://doi.org/10.3390/pr9081370

  • Yong, Y. K., Tan, J. J., Teh, S. S., Mah, S. H., Ee, G. C. L., Chiong, H. S., & Ahmad, Z. (2013). Clinacanthus nutans extracts are antioxidant with antiproliferative effect on cultured human cancer cell lines. Evidence-Based Complementary and Alternative Medicine, 2013. https://doi.org/10.1155/2013/462751

Elephantopus tomentosus

A widely used medicinal herb in Asia for the treatment of pain and inflammatory conditions such as wounds and bacterial skin infection.

Chinese Name: 白花地胆草Bái huā dì dǎn cǎo

Contains epifriedelanol, lupeol, 6-deoxyisojacreubin, butulinic acid, ursolic acid, ferulic acid, 3-formylindole, pinellic acid, 30- oxo-lup, 2b-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate, 2-dethoxy-2-hydroxyphantomolin, tomenphantopin A, B, H, tomenphantin A and B.

Native: North America

Plant Description: Perennial herb with leaves of various sizes that forms at the base of the plant.

Please reference published research

Please reference published research

  • Yam, M. F., Ang, L. F., Ameer, O. Z., Salman, I. M., Aziz, H. A., & Asmawi, M. Z. (2009). Anti-inflammatory and Analgesic Effects of Elephantopus tomentosus Ethanolic Extract. Journal of Acupuncture and Meridian Studies, 2(4), 280–287. https://doi.org/10.1016/s2005-2901(09)60069-8

  • Yam, M. F., Basir, R., Asmawi, M. Z., Rosidah, Ahmad, M., & Akowuah, G. A. (2008). Antioxidant and Hepatoprotective Activities ofElephantopus tomentosus. Ethanol Extract. Pharmaceutical Biology, 46(3), 199–206. https://doi.org/10.1080/13880200701735569

HOUTTUYNIA CORDATA

Houttuynia cordata has long been used as a medicinal herb and food garnish in Southeast Asia. The plant is also commonly known as fish wort or heart leaf due to its heart-shaped leaves. Used in Traditional Chinese medicine to treat lung abscess, cough, yellow sticky sputum, bronchitis, dyspnea and pneumonia. 

Chinese Name: 鱼腥草 Yú xīng cǎo

Contains rutin, hyperin, afzelin, quercitrin, isoquercitrin, quercetin, kaempferol, phloridzin, avicularin, chlorogenic acid, cryptochlorogenic acid, neochlorogenic acid, procyanidin B, catechin, quinic acic, caffeic acid and over 20 amino acids including alanine, valine, glutamic acid, aspartic acid and isoleucine.

Native: East Asia, Bhutan, Nepal

Plant Description: Perennial plant with distinctive heart-shaped leaves and tail-like rhizome.

Please refer to publish reference

Please refer to published reference

  • Laldinsangi, C. (2022). The therapeutic potential of Houttuynia cordata: A current review. Heliyon, e10386. https://doi.org/10.5066/F7KH0KBK.

  • Lee, J. H., Ahn, J., Kim, J. W., Lee, S. G., & Kim, H. P. (2015). Flavonoids from the aerial parts of Houttuynia cordata attenuate lung inflammation in mice. Archives of Pharmacal Research, 38(7), 1304–1311. https://doi.org/10.1007/s12272-015-0585-8

  • Ling, L. J., Lu, Y., Zhang, Y. Y., Zhu, H. Y., Tu, P., Li, H., & Chen, D. F. (2020). Flavonoids from Houttuynia cordata attenuate H1N1-induced acute lung injury in mice via inhibition of influenza virus and Toll-like receptor signalling. Phytomedicine, 67, 153150. https://doi.org/10.1016/j.phymed.2019.153150

  • Nuengchamnong, N., Krittasilp, K., & Ingkaninan, K. (2009). Rapid screening and identification of antioxidants in aqueous extracts of Houttuynia cordata using LC–ESI–MS coupled with DPPH assay. Food Chemistry, 117(4), 750–756. https://doi.org/10.1016/j.foodchem.2009.04.071