PHYTOR RESTORE COLON ACTIVE INGREDIENTS

Each of Our Curated Ingredient Contains in Excess of 3,000 Active Plant Compounds

From these we have isolated specific active ingredients which deliver targeted health benefits. We have shared our herbal formulations with over 10,000 patients who seek to use natural remedies to support their body’s natural healing abilities.

CLINACANTHUS NUTANS

Traditionally used as herbal medicines in Thailand, Malaysia, Indonesia and China, extensive studies on the herb had started since the late 1980s. The herb has been of great interest to researchers for its folk use in various diseases such as kidney and liver issues, irregular periods, skin rashes, varicella-zoster virus lesions, dysentery and cancer.

Chinese Name:

忧遁草 Yōu dùn cǎo

Contains stigmasterol, lupeol, β-Sitosterol, betulin, C-glycosyl flavones (vitexin, isovitexin, shaftoside, isomollupentin 7-O-β-glucopyranoside, orientin and isoorientin), nine cerebrosides and monoacylmonogalactoylglycerol; as well as chlorophyll derivatives.

Native: Thailand, Malaysia, Indonesia, China

Habitat: Wet forests and plains, mainly cultivated.

Plant Description: Scandent shrub with upright branches and narrow, oblong leaves.

Please refer to the published research

Ong, W. Y., Herr, D. R., Sun, G. Y., & Lin, T. N. (2022). Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans. Molecules, 27(11), 3607. DOI: https://doi.org/10.3390/molecules27113607
Chia, T. Y., Gan, C. Y., Murugaiyah, V., Hashmi, S. F., Fatima, T., Ibrahim, L., … & Ahmad, A. (2021). A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine. Molecules, 27(1), 139. DOI:https://doi.org/10.3390/molecules27010139
Mahmod, I. I., Ismail, I. S., Alitheen, N. B., Normi, Y. M., Abas, F., Khatib, A., & Latip, J. (2020). NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition. BMC complementary medicine and therapies, 20(1), 1-18. DOI: http://dx.doi.org/10.1186/s12906-020-03067-3
Alam, A., Ferdosh, S., Ghafoor, K., Hakim, A., Juraimi, A. S., Khatib, A., & Sarker, Z. I. (2016). Clinacanthus nutans: A review of the medicinal uses, pharmacology and phytochemistry. Asian Pacific journal of tropical medicine, 9(4), 402-409. DOI:https://doi.org/10.1016/j.apjtm.2016.03.011

LEEA INDICA

Leea Indica, otherwise known as “Bandicoot Berry” is a large shrub in the family Vitaceae – a plant family known for its fruit crop. The whole plant is traditionally used in India to treat headache, joint or body pain, rheumatism and skin issues. It was one of the seven medicinal plants studied by a team of NUS researchers over 3-years period between 2010 and 2013 for potential cancer-fighting properties.

Chinese Name:

火筒树 Huǒ tǒng shù

Contains 31 compounds of different classes, including β-Sitosterol, Lupeol, Di-n-octyl, β-Amyrin, Gallic acid, Quercitrin, Dibutyl phthalate, α-Tocopherol, Di-iso butyl phthalate, Di-n-butyl phthalate, N-butyl iso butyl phthalate, Mollic acid arabinoside, Phthalic acid, Palmitic acid, Eicosanol, Solanesol, Farnesol, Ursolic acid and N-butyl gallate.

Native: Indomalaya, Indochina, Australia, Pacific Islands

Habitat: Wet forests and plains, mainly cultivated.

Plant Description: Large evergreen perennial shrubs with twice or thrice pinnate leaves.

Please refer to the published research

Siew, Y. Y., Yew, H. C., Neo, S. Y., Seow, S. V., Lew, S. M., Lim, S. W., … & Koh, H. L. (2019). Evaluation of anti-proliferative activity of medicinal plants used in Asian Traditional Medicine to treat cancer. Journal of ethnopharmacology, 235, 75-87. https://doi.org/10.1016/j.jep.2018.12.040
Mishra, G., Khosa, R. L., Singh, P., & Tahseen, M. A. (2016b). Ethnobotany and phytopharmacology of Leea indica: An overview. Journal of Coastal Life Medicine, 4(1), 69–72. https://doi.org/10.12980/jclm.4.2016jclm-2014-0017
Rahman, M. A., Imran, T. B., & Islam, S. (2013). Antioxidative, antimicrobial and cytotoxic effects of the phenolics of Leea indica leaf extract. Saudi Journal of Biological Sciences, 20(3), 213–225. https://doi.org/10.1016/j.sjbs.2012.11.007
Hossain, F., Mostofa, M. G., & Alam, A. K. (2021). Traditional uses and pharmacological activities of the genus leea and its phytochemicals: A review. Heliyon, 7(2), e06222. https://doi.org/10.1016/j.heliyon.2021.e06222
Singh, D., Siew, Y. Y., Chong, T. I., Yew, H. C., Ho, S. S. W., Lim, C. S. E. S., … & Koh, H. L. (2019). Identification of phytoconstituents in Leea indica (Burm. F.) Merr. leaves by high performance liquid chromatography micro time-of-flight mass spectrometry. Molecules, 24(4), 714. https://doi.org/10.3390/molecules24040714

Strobilanthes crispus

Traditionally used in Indonesia and Malaysia to treat urinary stones, gallbladder stones, difficult urination, hemorrhoid, constipation, or for diuretic purpose. It was one of the seven medicinal plants studied by a team of NUS researchers over 3-years period between 2010 and 2013 for potential cancer-fighting properties

Chinese Name:

黑面将军 Hēi miàn jiāng jūn

Contains p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, vanillic acid, gentinic acid, ferulic acid, syryngic acid, tannin alkaloid, catechin, rutin, myricetin, luteolin, apigenin, naringenin and kaempferol

Native: Madagascar, Indonesia, Malaysia

Plant Description: Shrub with dark green shiny leaves occurring in pairs in opposite leaf arrangement.

Please refer to the published research

Gul, M. T., Dheyab, A. S., Shaker, E. K., Muhammad, N., & Pauzi, A. N. (2020). In vitro evaluation of anti-urolithiatic properties of Strobilanthes crispus extracted using different solvents. Research Journal of Chemistry and Environment Vol, 24, 1.
Ban, W. K., Fong, I. L., Khong, H. Y., & Phung, J. H. Y. (2022). Wound Healing, Antimicrobial and Antioxidant Properties of Clinacanthus nutans (Burm. f.) Lindau and Strobilanthes crispus (L.) Blume Extracts. Molecules, 27(5), 1722. DOI: https://doi.org/10.3390/molecules27051722
Tobing, J. H. (2022). The Effect of Sambiloto (Andrographis paniculata Nees.) and Kejibeling (Strobilanthes crispa) Leaves on Uric Acid Levels of White Rats (Rattus norvegicus). 8ISC Proceedings: Sciences, 5-12. http://ejournal.unklab.ac.id/index.php/8ISCSC/article/view/668

- Chong, H. Z., Rahmat, A., Yeap, S. K., Md Akim, A., Alitheen, N. B., Othman, F., & Gwendoline-Ee, C. L. (2012). In vitro cytotoxicity of Strobilanthes crispus ethanol extract on hormone dependent human breast adenocarcinoma MCF-7 cell. BMC Complementary and Alternative Medicine, 12(1). https://doi.org/10.1186/1472-6882-12-35
- Ng, M. G., Ng, C. H., Ng, K. Y., Chye, S. M., Ling, A. P. K., & Koh, R. Y. (2021). Anticancer Properties of Strobilanthes crispus: A Review. Processes, 9(8), 1370. https://doi.org/10.3390/pr9081370
- Norfarizan, N., Asmah, R., Rokiah, M., Fauziah, O., & Faridah, H. (2009). Effects of Strobilanthes crispus Juice on Wound Healing and Antioxidant Enzymes in Normal and Streptozotocin-Induced Diabetic Rats. Journal of Biological Sciences, 9(7), 662–668. https://doi.org/10.3923/jbs.2009.662.668

Elephantopus tomentosus

A widely used medicinal herb in Asia for the treatment of pain and inflammatory conditions such as wounds, tonsillitis and various respiratory disorders.

Chinese Name:

白花地胆草Bái huā dì dǎn cǎo

Contains epifriedelanol, lupeol, 6-deoxyisojacreubin, butulinic acid, ursolic acid, ferulic acid, 3-formylindole, pinellic acid, 30- oxo-lup, 2b-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate, 2-dethoxy-2-hydroxyphantomolin, tomenphantopin A, B, H, tomenphantin A and B.

Native: North America

Plant Description: Perennial herb with leaves of various sizes that forms at the base of the plant.

Please refer to the published research

Yam, M. F., Ang, L. F., Ameer, O. Z., Salman, I. M., Aziz, H. A., & Asmawi, M. Z. (2009). Anti-inflammatory and Analgesic Effects of Elephantopus tomentosus Ethanolic Extract. Journal of Acupuncture and Meridian Studies, 2(4), 280–287. https://doi.org/10.1016/s2005-2901(09)60069-8
Yam, M. F., Basir, R., Asmawi, M. Z., Rosidah, Ahmad, M., & Akowuah, G. A. (2008). Antioxidant and Hepatoprotective Activities ofElephantopus tomentosus. Ethanol Extract. Pharmaceutical Biology, 46(3), 199–206. https://doi.org/10.1080/13880200701735569

Callicarpa formosana

A species of beautyberry with centuries of use in Traditional Chinese Medicine for the prevention and treatment of inflammation, rheumatism and gastrointestinal bleeding. Pharmacological studies on the Callicarpa species has validated its use valias a traditional medicine and revealed good efficacy on clinical applications of inflammation, internal and external haemorrhage.

Chinese Name:

紫珠 Zǐ zhū

Contains 3,5,7,4′-tetramethoxyflavone, 3,5,7,3′,4′-pentamethoxyflavone, 5-hydroxy-3,4,7,3′-tetramethoxyflavone, 3,4,7,3′-tetramethoxyflavone, 2α,3α-dihydroxyursene-28-acid and ursolic acid.

Native: China, Japan, Philippines, Taiwan

Plant Description: Deciduous shrub with showy purple fruits.

Please refer to the published research

Tu, Y., Sun, L., Guo, M., & Chen, W. (2013). The medicinal uses of Callicarpa L. in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review. Journal of Ethnopharmacology, 146(2), 465–481. https://doi.org/10.1016/j.jep.2012.12.051
Jones, W., & Kinghorn, A. (2008). Biologically Active Natural Products of the Genus Callicarpa. Current Bioactive Compounds, 4(1), 15–32. https://doi.org/10.2174/157340708784533393